Dimethyl sulfoxide, DMSO
Name Reactions
Recent Literature
Oxidation of alkynes to α-dicarbonyl derivatives through a convenient
one-pot procedure via a Brřnsted acid-promoted "hydration" and a
DMSO-based oxidation sequence has been achieved in high yields.
Z. Wan, C. D. Jones, D. Mitchell, J. Y. Pu, T. Y. Zhang, J. Org. Chem.,
2006,
71, 826-828.
Selective and quantitative conversion of thiols to disulfides was effected
by dimethyl sulfoxide under mild conditions catalyzed by
dichlorodioxomolybdenum(VI).
R. Sanz, R. Aguado, M. R. Pedrosa, F. Arnáiz, Synthesis,
2002, 856-858.
"Activated" dimethyl sulfoxide efficiently dehydrogenates hydrazones to the
respective diazo compounds at -78°C. Under optimized conditions, simple vacuum
filtration provides solutions of pure diazo compounds from which stable diazo
species can be isolated in high yield, or that can be directly used in
subsequent reactions.
M. I. Javed, M. Brewer, Org. Lett., 2007,
9, 1789-1792.
