Magnesium
Name Reactions
Recent Literature
An intermolecular pinacol coupling of aromatic or aliphatic carbonyl
compounds catalyzed by a complex of samarium diiodide (SmI2) with
tetraglyme in the presence of Me2SiCl2 and Mg is
described. High diastereoselectivity has been achieved in reactions with
aliphatic and aromatic aldehydes. De values
of up to 99% have been achieved in intramolecular pinacol coupling reactions.
H. C. Aspinall, N. Greeves, C. Valla, Org. Lett., 2005, 7, 1919-1922.
Rieke Ni generated in situ was able to promote the pinacol coupling of
various carbonyls efficiently. Another catalytically effective, cheaper
and more convenient NiCl2(Cat.)/Mg/TMSCl system was designed
and developed further successfully. Single-electron transfer (SET)
mechanisms for the coupling reactions and the DL/meso
diastereoselectivity were also explained.
L. Shi, C.-A. Fan, Y.-Q. Tu, M. Wang, F.-M. Zhang, Tetrahedron,
2004, 60, 2851-2855.
Magnesium in methanol is an effective reagent for the chemoselective
reduction of ozonides and other peroxides. Mg/MeOH is significantly more
reactive than Me2S or PPh3 and somewhat more
reactive than Zn/HOAc.
P. Dai, P. H. Dussault, T. K. Trullinger, J. Org. Chem., 2004, 69, 2851-2852.
