Categories: C-F Bond Formation >
Synthesis of fluoroarenes
Name Reactions
Recent Literature
Functionalized aryl- or heteroarylmagnesium reagents, prepared from the
corresponding bromides or iodides using halogen-magnesium exchange or direct
magnesium insertion in the presence of lithium chloride, reacted smoothly with
N-fluorobenzenesulfonimide to give the corresponding aromatic fluorides
in good yields.
S. Yamada, P. Knochel, Synthesis, 2010,
2490-2494.
Drawbacks associated with the classic Balz-Schiemann reaction are eliminated
in a series of examples by conducting fluorodediazoniation in ionic liquid
solvents.
K. K. Laali, V. J. Gettwert, Journal of Fluorine Chemistry, 2001,
107, 31-34.
