Desulfonation

Recent Literature

Alkali metals absorbed into nanostructured silica (M-SG) were found to be useful solid-state reagents for the desulfonation of a range of N,N-disubstituted sulfonamides. M-SG reagents are room-temperature-stable free-flowing powders that retain the chemical reactivity of the parent metal, decreasing the danger and associated cost of using reactive metals.
P. Nandi, M. Y. Redko, K. Petersen, J. L. Dye, M. Lefenfeld, P. F. Vogt, J. E. Jackson, Org. Lett., 2008, 10, 5441-5444.

A low-valent titanium generated in situ from Ti(O-i-Pr)₄, Me₃SiCl, and Mg powder in THF reacted with a broad range of sulfonamides in a reductive bond cleaving pathway to provide the corresponding amines, hydrocarbons and thiols. The reagent could also cleave sulfonates to the corresponding alcohols.
N. Shohji, T. Kawaji, S. Okamoto, Org. Lett., 2011, 13, 2626-2629.