Synthesis of Trisulfides

Recent Literature

A straightforward preparation of 1-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)trisulfanyl]dodecane from readily available substrates, followed by reaction with aliphatic and aromatic thiols enables the synthesis of unsymmetrical trisulfides under mild conditions in very good yields.
S. Lach, M. Sliwka-Kaszynska, D. Witt, Synlett, 2010, 2857-2860.

Convenient methods for the synthesis of symmetrical trisulfides from aliphatic and aromatic thiols under mild conditions are based on the straightforward preparation of (5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorin-2-yl)disulfanyl derivatives from readily available 5,5-dimethyl-2-sulfanyl-2-thioxo-1,3,2-dioxaphosphorinane or bis(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl) disulfide.
A. Kertmen, S. Lach, J. Rachon, D. Witt, Synthesis, 2009, 1459-1462.