Categories: Synthesis of N-Heterocycles >
Synthesis of 1,2-dihydroquinolines
Recent Literature
An efficient synthetic route to 1,2-dihydroquinolines relies on
AuCl3/AgSbF6-catalyzed intramolecular allylic amination of
2-tosylaminophenylprop-1-en-3-ols in good yields. The method was shown to be
applicable to a broad range of 2-tosylaminophenylprop-1-en-3-ols containing
electron-withdrawing, electron-donating, and sterically demanding substrate
combinations.P. Kothandaraman, S. J. Foo, P. W. H. Chan, J. Org. Chem., 2009,
74, 5947-5952.
