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Synthesis of 2-pyrrolines

Recent Literature

An efficient, scalable and mild cyclocarboamination reaction of nonactivated alkynes with aziridines, catalyzed by low loadings of Lewis or Bronsted acids, provides a wide range of polysubstituted 2,3-dihydropyrroles in a highly regioselective manner through a formal [3+2] cycloaddition.
P. A. Wender, D. Strand, J. Am. Chem. Soc., 2009, 131, 7528-7529.