Categories: Synthesis of N-Heterocycles >
Synthesis of maleimides
Recent Literature
Intermolecular [2 + 2 + 1] ruthenium-catalyzed cocyclization of isocyanates,
alkynes, and CO proceeded smoothly in mesitylene at 130°C to give a variety of
polysubstituted maleimides in excellent yields with high selectivity.
T. Kondo, M. Nomura, Y. Ura, K. Wada, T. Mitsudo, J. Am. Chem. Soc., 2006, 128, 14816-14817.
Unsymmetrical 3,4-disubstituted maleimides have been synthesized by
palladium-catalyzed cross-coupling reactions of indium organometallics with
3,4-dihalomaleimides.Various alkyl, aryl, heteroaryl, and alkynyl 3,4-disubstituted maleimides
have been prepared in good yields
and with high selectivity.
L. Bouissane, J. P. Sestelo, L. A. Sarandeses, Org. Lett., 2009,
11, 1285-1288.
Unsymmetrical 3,4-disubstituted maleimides have been synthesized by
palladium-catalyzed cross-coupling reactions of indium organometallics with
3,4-dihalomaleimides.Various alkyl, aryl, heteroaryl, and alkynyl 3,4-disubstituted maleimides
have been prepared in good yields
and with high selectivity.
L. Bouissane, J. P. Sestelo, L. A. Sarandeses, Org. Lett., 2009,
11, 1285-1288.
