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Synthesis of tetrazoles

Recent Literature

A series of 1-substituted 1H-1,2,3,4-tetrazole compounds have been synthesized in good yields from amines, triethyl orthoformate, and sodium azide through the catalyzed reaction with Yb(OTf)₃.
W.-K. Su, Z. Hong, W.-G. Shan, X.-X. Zhang, Eur. J. Org. Chem., 2006, 2723-2726.

A series of primary alcohols and aldehydes were treated with iodine in ammonia water under microwave irradiation to give the intermediate nitriles, which without isolation underwent [2 + 3] cycloadditions with dicyandiamide and sodium azide to afford the corresponding triazines and tetrazoles in high yields.
J.-J. Shie, J.-M. Fang, J. Org. Chem., 2007, 72, 3141-3144.

J.-J. Shie, J.-M. Fang, J. Org. Chem., 2007, 72, 3141-3144.

A general method for the synthesis of 1,5-disubstituted tetrazoles from imidoylbenzotriazoles involves mild reaction conditions and short reaction times.
A. R. Katritzky, C. Cai, N. K. Meher, Synthesis, 2007, 1204-1208.

A versatile and highly efficient Zn(OTf)₂-catalyzed one-pot reaction of alkenes, NBS, nitriles, and TMSN₃ gives various 1,5-disubstituted tetrazoles containing an additional α-bromo functionality of the N1-alkyl substituent.
S. Hajra, D. Sinha, M. Bhowmick, J. Org. Chem., 2007, 72, 1852-1855.

Pyridine N-oxides were converted to tetrazolo[1,5-a]pyridines in good yield in the presence of sulfonyl or phosphoryl azides and pyridine by heating in the absence of solvent. Diphenyl phosphorazidate (DPPA) was the most convenient reagent.
J. M. Keith, J. Org. Chem., 2006, 71, 9540-9543.