Syntheses of FDA approved HIV protease inhihitors.

A. K. Ghosh, G. Bilcer, G. Schiltz, Synthesis, 2001, 2203.

Key Words:
HIV; protease; inhibitor; isostere; synthesis; ALPHA-AMINO ALDEHYDES; HYDROXYETHYLENE DIPEPTIDE ISOSTERES; DIASTEREOSELECTIVE SYN-EPOXIDATION; PROTEINASE-INHIBITOR RO-31-8959; IMMUNODEFICIENCY-VIRUS PROTEASE; ORALLY BIOAVAILABLE INHIBITOR; LARGE-SCALE SYNTHESIS; KEY BUILDING-BLOCK; STEREOSELECTIVE SYNTHESIS; PRACTICAL SYNTHESIS



cis-1-Aminoindan-2-ol in asymmetric syntheses.

A. K. Ghosh, S. Fidanze, C. H. Senanayake, Synthesis, 1998, 937.

Key Words:
asymmetric synthesis/1-aminoindan-2-ol/protease/inhibitor/HIV-1 PROTEASE INHIBITORS/DIELS-ALDER REACTION/HYDROXYETHYLENE DIPEPTIDE ISOSTERES/HUMAN-IMMUNODEFICIENCY-VIRUS/ENANTIOSELECTIVE BORANE REDUCTION/RESISTANCE REVERSING ACTIVITY/EFFICIENT CHIRAL AUXILIARY/RAY CRYSTAL-STRUCTURE/ORGANIC-SYNTHESIS/C-2-SYMMETRICAL BIS(OXAZOLINES)



Tartaric acid and tartrates in the synthesis of bioactive molecules.

A. K. Ghosh, E. S. Koltun, G. Bilcer, Synthesis, 2001, 1281.

Key Words:
tartaric acid; tartrate; synthesis; natural products; bioactive; STEREOSELECTIVE TOTAL SYNTHESIS; RING-CLOSING METATHESIS; ASYMMETRIC-SYNTHESIS; PANAX-GINSENG; ENANTIOSELECTIVE SYNTHESIS; ABSOLUTE-CONFIGURATION; NITRONE CYCLOADDITION; OLEFIN METATHESIS; ORGANIC-SYNTHESIS; NATURAL-PRODUCTS



C-2-symmetric chiral bis(oxazoline)-metal complexes in catalytic asymmetric synthesis.

A. K. Ghosh, P. Mathivanan, J. Cappiello, Tetrahedron: Asymmetry, 1998, 9, 1.

Key Words:
DIELS-ALDER REACTIONS/BIS-OXAZOLINE LIGANDS/FIRST ENANTIOSELECTIVE SYNTHESIS/FUNCTIONALLY-SUBSTITUTED ARYL/COPPER-COMPLEXES/INTRAMOLECULAR CYCLOPROPANATION/BISOXAZOLINE LIGANDS/DANISHEFSKYS DIENE/RADICAL REACTIONS/ALDOL REACTIONS