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Cobalt-Catalyzed Hydroazidation of Olefins: Convenient Access to Alkyl Azides

Jérôme Waser, Hisanori Nambu and Erick M. Carreira*

*Laboratorium für Organische Chemie, ETH Hönggerberg, CH-8093 Zürich, Switzerland, Email: carreiraorg.chem.ethz.ch

J. Waser, H. Nambu, E. M. Carreira, J. Am. Chem. Soc., 2005, 127, 8294-8295.

DOI: 10.1021/ja052164r (free Supporting Information)


Abstract

A highly Marknovikov selectiv conversion of various olefins to azides was achieved using a cobalt catalyst, 3 equiv of TsN3 as nitrogen source and simple silanes (PhSiH3, TMDSO).

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Cobalt-Catalyzed Synthesis of Tertiary Azides from α,α-Disubstituted Olefins under Mild Conditions Using Commercially Available Reagents

B. Gaspar, J. Waser, E. M. Carreira, Synthesis, 2007, 3839-3845.


Key Words

Alkyl Azides, Phenylsilane, Tetramethyldisiloxane (TMDSO)


ID: J48-Y2005-2390