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Organomediated Morita-Baylis-Hillman Cyclization Reactions

Marie E. Krafft* and Thomas F. N. Haxell

*Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306, Email: mekchem.fsu.edu

M. E. Krafft, T. F. N. Haxell, J. Am. Chem. Soc., 2005, 127, 10168-10169.

DOI: 10.1021/ja052146+ (free Supporting Information)


Abstract

An organomediated, intramolecular Morita-Baylis-Hillman reaction of molecules bearing allylic leaving groups as the electrophilic partner provided a facile, high yielding, straightforward synthesis of densely functionalized cyclic molecules.

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Organocatalysis of the Morita-Baylis-Hillman Alkylation Using Trialkylphosphines

M. E. Krafft, K. A. Seibert, Synlett, 2006, 3334-3336.


Key Words

Baylis-Hillman Reaction, Organocatalysis, Cyclopentenes, Cyclohexenes, Enones


ID: J48-Y2005-2460