Brønsted Guanidine Acid-Base Ionic Liquids: Novel Reaction Media for the Palladium-Catalyzed Heck Reaction
Shenghai Li, Yingjie Lin, Haibo Xie, Suobo Zhang* and Jianing Xu
*State Key Laboratory of Polymer and Chemistry, Changchun Institute of Applied Chemistry, Changchun 130022, China, Email: sbzhangciac.jl.cn
S. Li, Y. Lin, H. Xie, S. Zhang, J. Xu, Org. Lett., 2006, 8, 391-394.
DOI: 10.1021/ol052543p (free Supporting Information)
Brønsted acid-base ionic liquids (GILs) based on guanidine and acetic acid are efficient and reusable reaction media for palladium-catalyzed Heck reactions. These solvents play multiple roles: as strong bases and as ligands to stabilize Pd species.
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S. Li, Y. Lin, J. Cao, S. Zhang, J. Org. Chem., 2007, 72, 4067-4072.