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Combined C-H Functionalization/C-N Bond Formation Route to Carbazoles

W. C. Peter Tsang, Nan Zheng and Stephen L. Buchwald*

*Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Email: sbuchwalmit.edu

W. C. P. Tsang, N. Zheng, S. L. Buchwald, J. Am. Chem. Soc., 2005, 127, 14560-14561.

DOI: 10.1021/ja055353i (free Supporting Information)


Abstract

A palladium-catalyzed tandem directed C-H functionalization and amide arylation gave a series of substituted carbazoles. The Pd(0) species generated are reoxidized to Pd(II) in the presence of Cu(OAc)2 and an atmosphere of oxygen.

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Key Words

Carbazoles


ID: J48-Y2005-2640