Synthesis of 2,3-Disubstituted Benzofurans by Platinum-Olefin-Catalyzed Carboalkoxylation of o-Alkynylphenyl Acetals
Itaru Nakamura, Yuya Mizushima and Yoshinori Yamamoto*
*Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan, Email: yoshimail.tains.tohoku.ac.jp
I. Nakamura, Y. Mizushima, Y. Yamamoto, J. Am. Chem. Soc., 2005, 127, 15022-15023.
DOI: 10.1021/ja055202f
Abstract
The Pt-catalyzed cyclization of o-alkynylphenyl acetals produces 3-(-alkoxyalkyl)benzofurans in good to high yields. The mechanism is discussed.
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ID: J48-Y2005-2720