Enantioselective One-Pot Three-Component Synthesis of Propargylamines
Alakesh Bisai and Vinod K. Singh*
*Department of Chemistry, Indian Institute of Technology, Kanpur, India 208
016, Email: vinodks
iitk.ac.in
A. Bisai, V. K. Singh, Org. Lett., 2006, 8, 2405-2408.
DOI: 10.1021/ol060793f (free Supporting Information)
Abstract
A copper(I) complex of i-Pr-pybox-diPh efficiently catalyzes the enantioselective one-pot three-component synthesis of propargylamines from aromatic aldehydes, anilines, and alkynes. A transition-state model has been proposed.
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Key Words
Propargylic Amines, Multicomponent Reactions
ID: J54-Y2006-1420
