Strecker Reaction of Aldimines Catalyzed by a Nucleophilic N-Heterocyclic Carbene
Yoshimasa Fukuda, Yuka Maeda, Kazuhiro Kondo*, Toyohiko Aoyama*
*Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan, Email: kazukphar.nagoya-cu.ac.jp, aoyamaphar.nagoya-cu.ac.jp
Y. Fukuda, Y. Maeda, K. Kondo, T. Aoyama, Synthesis, 2006, 1937-1939.
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The first method for Strecker reaction of aldimines with TMSCN in the presence of a N-heterocyclic carbene as a nucleophilic catalyst is described.
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