Organic Chemistry Portal

Abstracts

Search:

Proline/Pipecolinic Acid-Promoted Copper-Catalyzed P-Arylation

Cheng Huang, Xu Tang, Hua Fu,* Yuyang Jiang and Yufen Zhao

*Key Laboratory of Chemical Biology, Guangdong Province, Graduate School of Shenzhen, Tsinghua University, Shenzhen 518057, P. R. China, Email: fuhuamail.tsinghua.edu.cn

C. Huang, X. Tang, H. Fu, Y. Jiang, Y. Zhao, J. Org. Chem., 2006, 71, 5020-5022.

DOI: 10.1021/jo060492j (free Supporting Information)


Abstract

A convenient and efficient copper-catalyzed approach for P-arylation of organophosphorus compounds containing P-H uses the commercially available and inexpensive proline and pipecolinic acid as ligands. The method can provide an entry to arylphosphonates, arylphosphinates and arylphosphine oxides.

see article for more examples

see article for more reactions



Key Words

phosphonates, phosphinates, phosphine oxides


ID: J42-Y2006-1750