Asymmetric Synthesis of Protected Arylglycines by Rhodium-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters
Melissa A. Beenen, Daniel J. Weix and Jonathan A. Ellman*
*Department of Chemistry, University of California, Berkeley, California
94720, Email: jellman
berkeley.edu
M. A. Beenen, D. J. Weix, J. A. Ellman, J. Am. Chem. Soc., 2006, 128, 6304-6305.
DOI: 10.1021/ja060529h (free Supporting Information)
Abstract
A new method for the Rh(I)-catalyzed addition of arylboronic acids to chiral N-tert-butanesulfinyl imino esters allows the asymmetric synthesis of arylglycine derivatives in high yields and diastereoselectivities for various functionalized arylboronic acids.
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Key Words
ID: J48-Y2006-2050
