Ru-Catalyzed Cyclization of Terminal Alkynals to Cycloalkenes
Jesús A. Varela, Carlos González-Rodríguez, Silvia G. Rubín, Luis Castedo and Carlos Saá*
*Departamento de Química Orgánica y Unidad Asociada al CSIC, Facultad de
Química, Universidad de Santiago de Compostela, 15782 Santiago de Compostela,
Spain, Email: qocsaa
usc.es
J. A. Varela, C. González-Rodríguez, S. G. Rubín, L. Castedo, Carlos Saá, J. Am. Chem. Soc., 2006, 128, 9576-9577.
DOI: 10.1021/ja0610434 (free Supporting Information)
Abstract
Cycloalkenes can be efficiently prepared by a new Ru-catalyzed decarbonylative cyclization of terminal alkynals. Under appropriate conditions, cycloisomerizations to conjugated aldehydes may be observed. Both processes involve catalytic Ru vinylidenes.
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proposed mechanism
Key Words
Cycloalkenes, Cyclopentenes, Cyclohexenes
ID: J48-Y2006-2280
