Highly Selective 1,6-Addition of Aryl Boronic Acids to α,β,γ,δ-Unsaturated Carbonyl Compounds Catalyzed by an Iridium Complex
Takahiro Nishimura, Yuichi Yasuhara, Tamio Hayashi*
*Department of Chemistry, Graduate School of Science, Sakyo, Kyoto 606-8502,
Japan, Email: thayashi
kuchem.kyoto-u.ac.jp
T. Nishimura, Y. Yasuhara, T. Hayashi, Angew. Chem. Int. Ed., 2006, 45, 5164-5166.
DOI: 10.1002/anie.200601719 (free Supporting Information)
Abstract
The catalytic iridium-catalyzed 1,6-addition of aryl boronic acids to electron-deficient dienes gave high yields of the corresponding δ-arylated carbonyl compounds with perfect 1,6-selectivity.
see article for more examples
Key Words
1,6-Additions (carbonyl compounds, carboxyl compounds), arylation, boronic acids, iridium, regioselectivity
ID: J06-Y2006-2190
