CoBr₂(Bpy): An Efficient Catalyst for the Direct Conjugate Addition of Aryl Halides or Triflates onto Activated Olefins

Muriel Amatore, Corinne Gosmini* and Jacques Périchon

*Laboratoire d'Electrochimie, Catalyse et Synthèse Organique, UMR 7582, Université Paris 12-C.N.R.S. 2, rue Henri Dunant, 94320 Thiais, France, Email: gosminiglvt-cnrs.fr

M. Amatore, C. Gosmini, J. Périchon, J. Org. Chem., 2006, 71, 6130-6134.

DOI: 10.1021/jo060855f

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Abstract

A conjugate addition of various aryl halides and triflates to Michael acceptors is efficiently catalyzed by CoBr₂(2,2'-bipyridine). The described procedure allows for the synthesis of 1,4-addition products in good yields.

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Key Words

1,4-Additions

ID: J42-Y2006-2360

CoBr2(Bpy): An Efficient Catalyst for the Direct Conjugate Addition of Aryl Halides or Triflates onto Activated Olefins

Muriel Amatore, Corinne Gosmini* and Jacques Périchon

CoBr₂(Bpy): An Efficient Catalyst for the Direct Conjugate Addition of Aryl Halides or Triflates onto Activated Olefins