Intermolecular Rhodium-Catalyzed Carbometalation/Heck-Type Reaction in Water
Takuya Kurahashi, Hiroshi Shinokubo* and Atsuhiro Osuka
*Department of Chemistry, Graduate School of Science, Kyoto University,
Sakyo-ku, Kyoto 606-8502, Japan, Email: hshino
kuchem.kyoto-u.ac.jp
T. Kurahashi, H. Shinokubo, A. Osuka, Angew. Chem. Int. Ed., 2006, 45, 6336-6338.
DOI: 10.1002/anie.200602585
Abstract
The rhodium-catalyzed reaction of aryl boronic acids with internal alkynes and acrylates in water gives the domino coupling products. The reaction demonstrates that water offers the possibility to discover novel transformations.
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Key Words
arenes, 1,3-dienes, alkynes, aqueous media, boron, domino reactions, multicomponent reactions, rhodium
ID: J06-Y2006-3030
