Gold(I)-Catalyzed Reaction of 1-(1-Alkynyl)-cyclopropyl Ketones with Nucleophiles: A Modular Entry to Highly Substituted Furans
Junliang Zhang, Hans-Günther Schmalz*
*Institut für Organische Chemie, Universität zu Köln, Greinstrasse 4, 50939 Köln, Germany, Email: schmalzuni-koeln.de
J. Zhang, H.-G. Schmalz, Angew. Chem. Int. Ed., 2006, 45, 6704-6707.
DOI: 10.1002/anie.200601252
Abstract
A mild, gold-catalyzed cascade reaction provides efficient access to highly substituted furans. The substrates can be readily prepared from the corresponding enones through cyclopropanation.
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Key Words
cyclopropanes, furans, gold, ring expansion, transition metals
ID: J06-Y2006-3270