Highly Enantioselective Transfer Hydrogenation of α,β-Unsaturated Ketones
Nolwenn J. A. Martin and Benjamin List*
*Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim an der Ruhr,
Germany, Email: list
mpi-muelheim.mpg.de
N. J. A. Martin, B. List, J. Am. Chem. Soc., 2006, 128, 13368-13369.
DOI: 10.1021/ja065708d
Abstract
An efficient and highly enantioselective conjugate transfer hydrogenation of α,β-unsaturated ketones is catalyzed by a salt made from tert-butyl valinate and a recently introduced powerful chiral phosphoric acid catalyst (TRIP).
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Key Words
Reduction of Enones, Organocatalysis, Hantzsch Ester
ID: J48-Y2006-3480
