Organic Chemistry Portal

Abstracts

Search:

Direct and Efficient One-Pot Preparation of Ketones from Aldehydes Using N-tert-Butylphenylsulfinimidoyl Chloride

James J. Crawford, Kenneth W. Henderson and William J. Kerr*

*Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, Scotland, U.K. G1 1XL, Email: w.kerrstrath.ac.uk

J. J. Crawford, K. W. Hederson, W. J. Kerr, Org. Lett., 2006, 8, 5073-5076.

DOI: 10.1021/ol061903l (free Supporting Information)


Abstract

A range of unsymmetrical ketones has been prepared in good yields from aldehydes in one simple synthetic operation by addition of organolithium compounds followed by an oxidation using  N-tert-butylphenylsulfinimidoyl chloride.

see article for more examples



Key Words

Ketones, N-tert-Butylphenylsulfinimidoyl Chloride


ID: J54-Y2006-3490