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Condensation of α-Aroylketene Dithioacetals and 2-Hydroxyarylaldehydes Results in Facile Synthesis of a Combinatorial Library of 3-Aroylcoumarins

H. Surya Prakash Rao* and S. Sivakumar

*Department of Chemistry, Pondicherry University, Pondicherry 605 014, India, E-mail: hspryahoo.com

H. S. P. Rao, S. Sivakumar, J. Org. Chem., 2006, 71, 8715-8723.

DOI: 10.1021/jo061372e (free Supporting Information)


Abstract

A facile, convenient, efficient, and high yielding synthesis of a combinatorial library of 3-aroylcoumarins has been developed by the condensation of easily available -aroylketene dithioacetals and 2-hydroxybenzaldehydes in the presence of catalytic amount of piperidine in THF reflux.

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Key Words

Coumarins


ID: J42-Y2006-3600