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Nickel-Catalyzed Addition of Alkynylboranes to Alkynes

Michinori Suginome,* Masamichi Shirakura and Akihiko Yamamoto

*Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University Katsura, Nishikyo-ku, Kyoto 615-8510, Japan, Email:

M. Suginome, M. Shirakura, A. Yamamoto, J. Am. Chem. Soc., 2006, 128, 14438-14439.

DOI: 10.1021/ja064970j (free Supporting Information)

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Alkynylboration of alkynes with alkynyl(pinacol)boranes in the presence of nickel catalysts gave cis-1-borylbut-1-en-3-yne derivatives. Some boryl-substituted enynes were reacted with sp2 halides under Suzuki-Miyaura coupling conditions.

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Key Words

Vinylboronates, Enynes

ID: J48-Y2006-3660