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A Mild and Regioselective Method for α-Bromination of β-Keto Esters and 1,3-Diketones Using Bromodimethylsulfonium Bromide (BDMS)

Abu T. Khan,* Md Ashif Ali, Papori Goswami and Lokman H. Choudhury

*Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India, E-mail: atkiitg.ernet.in

A. T. Khan, M. A. Ali, P. Goswami, L. H. Choudhury, J. Org. Chem., 2006, 71, 8961-8963.

DOI: 10.1021/jo061501r (free Supporting Information)


Abstract

1,3-keto esters and 1,3-diketones have been effectively and regioselectively α-monobrominated using bromodimethylsulfonium bromide as reagent.

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Key Words

α-Bromination (Ketones, Carboxylic Esters)


ID: J42-Y2006-3700