Triethanolamine as an Efficient and Reusable Base, Ligand and Reaction Medium for Phosphane-Free Palladium-Catalyzed Heck Reactions
Hong Ji Li, Lei Wang*
*Department of Chemistry, Huaibei Coal Teachers College, Huaibei, Anhui 235000, P. R. China, Email: leiwanghbcnc.edu.cn
H. J. Li, L. Wang, Eur. J. Org. Chem., 2006, 5101-5102.
DOI: 10.1002/ejoc.200600561 (free Supporting Information)
Triethanolamine was found to be an efficient and reusable base, ligand and reaction medium for phosphane-free palladium-catalyzed Heck reactions. The olefination of iodo- and bromoarenes generated the corresponding products in good to excellent yields. Triethanolamine could be recovered and recycled for five consecutive trials without significant loss of its reactivity.
see article for more examples
L. Zhou, L. Wang, Synthesis, 2006, 2649-2652.
Heck reaction, Palladium, Phosphane-free catalysis, Triethanolamine, Catalysis