Amberlite IRA900N3 as a New Catalyst for the Azidation of α,β-Unsaturated Ketones under Solvent-Free Conditions
Luca Castrica, Francesco Fringuelli,* Luisa Gregoli, Ferdinando Pizzo and Luigi Vaccaro*
*CEMIN-Dipartimento di Chimica, Università di Perugia, Via Elce di Sotto, 8, I-06123 Perugia, Italy, E-mail: luigiunipg.it, frifraunipg.it
L. Castrica, F. Fringuelli, L. Gregoli, F. Pizzo, L. Vaccaro, J. Org. Chem., 2006, 71, 9536-9539.
DOI: 10.1021/jo061791b
Abstract
Amberlite IRA900N3 is an excellent and recyclable organocatalyst for the azidation of α,β-unsaturated ketones with trimethylsilyl azide under solvent-free conditions. This procedure is a green tool for the preparation of β-azido ketones under mild conditions with good yields.
see article for more examples
Key Words
β-azido ketones, organocatalysis
ID: J42-Y2006-3960