Allylpalladium Umpolung in the Three-Component Coupling Synthesis of Homoallylic Amines
Chad D. Hopkins and Helena C. Malinakova*
*Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive,
Lawrence, Kansas 66045-7582, Email: hmalina
ku.edu
C. D. Hopkins, H. C. Malinakova, Org. Lett., 2006, 8, 5971-5974.
DOI: 10.1021/ol0624528 (free Supporting Information)
Abstract
Homoallylic α-amino esters and amines were prepared via a Pd(II)-catalyzed coupling of 1,2-nonadiene and boronic acids with ethyl iminoacetate or aliphatic, aromatic, and heteroaromatic imines.
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Key Words
Homoallylic Amines, Arenes, α-Amino Esters, Multicomponent Reactions
ID: J54-Y2006-4070
