Cu(I) Tol-BINAP-Catalyzed Enantioselective Michael Reactions of Grignard Reagents and Unsaturated Esters
Shun-Yi Wang, Shun-Jun Ji and Teck-Peng Loh*
*Division of Chemistry and Biological Chemistry, School of Physical and
Mathematical Sciences, Nanyang Technological University, Singapore 639798, Email:
teckpeng
ntu.edu.sg
S.-Y. Wang, S.-J. Ji, T.-P. Loh, J. Am. Chem. Soc., 2007, 129, 276-277.
DOI: 10.1021/ja0666046 (free Supporting Information)
Abstract
A highly efficient regio- and enantioselective catalytic asymmetric addition of Grignard regeants to α,β-unsaturated esters is promoted by the CuI-Tol-BINAP system.
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Key Words
ID: J48-Y2007-0000
