Copper-Carbene Complexes as Catalysts in the Synthesis of Functionalized Styrenes and Aliphatic Alkenes
Hélène Lebel,* Michaël Davi, Silvia Díez-Gonzlez and Steven P. Nolan
*Département de Chimie, Université de Montréal, P.O. Box 6128, Station
Downtown, Montréal, Québec, Canada, H3C 3J7, Email: helene.lebel
umontreal.ca
H. Lebel, M. Davi, S. Díez-Gonzlez, S. P. Nolan, J. Org. Chem., 2007, 72, 144-149.
DOI: 10.1021/jo061781a
Abstract
Inexpensive (NHC)-Cu complexes efficiently catalyzed the methylenation of various aliphatic and aromatic carbonyl compounds in the presence of trimethylsilyldiazomethane, triphenylphosphine, and 2-propanol. High yields were obtained for the formation of styrenes containing nitro, trifluoromethyl, amino, and ester groups.
see article for more examples
Rhodium-Catalyzed Methylenation of Aldehydes
A. Y. Koposov, R. R. Karimov, I. M. Geraskin, V. N. Nemykin, V. V. Zhdankin, J. Org. Chem., 2006, 72, 8452-8458.
Key Words
ID: J42-Y2007-0010
