Application of the Chiral Bis(phosphine) Monoxide Ligand to Catalytic Enantioselective Addition of Dialkylzinc Reagents to β-Nitroalkenes
Alexandre Côté, Vincent N. G. Lindsay and André B. Charette*
*Département de Chimie, Université de Montréal, P.O. Box 6128, Station Downtown, Montréal, Québec, Canada H3C 3J7, Email: andre.charetteumontreal.ca
A. Côté, V. N. G. Lindsay, A. B. Charette, Org. Lett., 2007, 9, 85-87.
DOI: 10.1021/ol062792t
Abstract
Me-DuPHOS monoxide is a very effective ligand in the enantioselective copper-catalyzed enantioselective addition of dialkylzinc reagents to β-nitroalkenes offering high yields of nitroalkanes, broad and complementary substrate scope, and high enantioselectivities.
see article for more examples
Key Words
ID: J54-Y2007-0130