o-Iodoxybenzoic Acid- and Tetraethylammonium Bromide-Mediated Oxidative Transformation of Primary Carboxamides to One-Carbon Dehomologated Nitriles
Dinesh S. Bhalerao, Ulhas S. Mahajan, Kiran H. Chaudhari and Krishnacharya G. Akamanchi*
*Department of Pharmaceutical Sciences & Technology, University Institute of
Chemical Technology, Matunga, Mumbai-400 019, India, Email:
kgap
rediffmail.com
D. S. Bhalarao, U. S. Mahajan, K. H. Chaudhari, K. G. Akamanchi, J. Org. Chem., 2007, 72, 662-665.
DOI: 10.1021/jo0619074 (free Supporting Information)
Abstract
A clean and efficient method for the oxidative transformations of primary carboxamides to one-carbon dehomologated nitriles using the combination of o-iodoxybenzoic acid and tetraethylammonium bromide exhibits a broad scope and is expected to be of great utility in organic synthesis.
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Key Words
ID: J42-Y2007-0240
