Three-Component Coupling Reactions of Thioformamides with Organolithium and Grignard Reagents Leading to Formation of Tertiary Amines and a Thiolating Agent
Toshiaki Murai* and Fumio Asai
*Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido,
Gifu 501-1193, Japan, Email: mtoshi
gifu-u.ac.jp
T. Murai, F. Asai, J. Am. Chem. Soc., 2007, 129, 780-781.
DOI: 10.1021/ja068523f (free Supporting Information)
Abstract
A highly efficient three-component coupling reaction between thioformamides and organolithium and Grignard reagents was developed. The generality of the process has been demonstrated by using various combinations of reactants and reagents.
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Key Words
Amines, Benzylamines, Grignard Reagents
ID: J48-Y2007-250
