Oxidative Conversion of Primary Alcohols, and Primary, Secondary, and Tertiary Amines into the Corresponding Nitriles with 1,3-Diiodo-5,5-dimethylhydantoin in Aqueous NH3
Shinpei Iida, Hideo Togo*
*Graduate School of Science and Technology, Chiba University, Yayoi-cho
1-33, Inage-ku, Chiba 263-8522, Japan, Email: togo
faculty.chiba-u.jp
S. Iida, H. Togo, Synlett, 2007, 407-410.
Abstract
Various primary alcohols, and primary, secondary, and tertiary amines were efficiently converted into the corresponding nitriles in good yields by oxidation with 1,3-diiodo-5,5-dimethylhydantoin (DIH) in aqueous ammonia at 60 °C.
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Key Words
primary alcohols, primary amines, secondary amines, tertiary amines, 1,3-diiodo-5,5-dimethylhydantoin, nitriles, aqueous ammonia
ID: J60-Y2007-0360
