Gold(I)-Catalyzed Enantioselective Intramolecular Hydroamination of Allenes
Rebecca L. LaLonde, Benjamin D. Sherry, Eun Joo Kang and F. Dean Toste*
*Department of Chemistry, University of California, Berkeley, California
94720, Email: fdtoste
berkeley.edu
R. L. LaLonde, B. D. Sherry, E. J. Kang, F. D. Toste, J. Am. Chem. Soc., 2007, 129, 2452-2453.
DOI: 10.1021/ja068819l (free Supporting Information)
Abstract
An asymmetric intramolecular hydroamination of allenes catalyzed by phosphinegold(I)-bis-p-nitrobenzoate complexes is applicable to the enantioselective formation of vinyl pyrrolidines and piperidines in high ee.
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Key Words
Hydroamination, Pyrrolidines, Piperidines, Allenes
ID: J48-Y2007-0750
