Gold(I)-Catalyzed Isomerization of Allenyl Carbinol Esters: An Efficient Access to Functionalized 1,3-Butadien-2-ol Esters
Andrea K. Buzas, Florin M. Istrate and Fabien Gagosz*
*Laboratoire de Synthèse Organique, UMR 7652 CNRS/Ecole Polytechnique, Ecole
Polytechnique, 91128 Palaiseau, France, Email: gagosz
dcso.polytechnique.fr
A. K. Buzas, F. M. Istrate, F. Gagosz, Org. Lett., 2007, 9, 985-988.
DOI: 10.1021/ol063031t
Abstract
A gold(I)-catalyzed rearrangement of diversely substituted allenyl carbinol esters allows the efficient, rapid, and stereoselective synthesis of various functionalized 1,3-butadien-2-ol esters via a new 1,3-shift of an ester moiety onto a gold-activated allene.
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Key Words
ID: J54-Y2007-0820
