Synthesis of Carbamates and Ureas Using Zr(IV)-Catalyzed Exchange Processes
Chong Han and John A. Porco, Jr*
*Department of Chemistry and Center for Chemical Methodology and Library
Development, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts
02215, Email: porco
bu.edu
C. Han, J. A. Porco, Jr, Org. Lett., 2007, 9, 1517-1520.
DOI: 10.1021/ol0702728 (free Supporting Information)
Abstract
Zirconium(IV)-catalyzed exchange processes of dialkyl carbonates and carbamates in the presence of amines gave carbamates and ureas using 2-hydroxypyridine (HYP) and 4-methyl-2-hydroxyquinoline (MeHYQ) as catalytic additives, respectively. A microwave acceleration effect was observed in Zr(IV)-catalyzed carbamate-urea exchange.
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Key Words
Carbamates, Ureas, Microwave Synthesis
ID: J54-Y2007-1120
