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A Novel One-Pot Synthesis of 4-Substituted 1,2,4-Triazolidine-3,5-diones

Shadpour Mallakpour*, Zahra Rafiee

*Organic Polymer Chemistry Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran, Email: mallakcc.iut.ac.ir

S. Mallakpour, Z. Rafiee, Synlett, 2007, 1255-1256.

DOI: 10.1055/s-2007-977413


Abstract

In a simple and one-pot pathway for the preparation of 4-substituted phenyl derivatives of triazolidindiones (urazoles), aniline derivatives were reacted with ethyl chloroformate to give the corresponding carbamate derivatives. The subsequent reaction with ethyl carbazide gave semicarbazides, which cyclized into triazolidindiones.

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Key Words

urazole derivatives, heterocyclic compounds, semi­carbazide, carbamate, one-pot reaction


ID: J60-Y2007-1510