An Efficient Route to Benzene and Phenol Derivatives via Ring-Closing Olefin Metathesis

Kazuhiro Yoshida*, Shingo Horiuchi, Noriyuki Iwadate, Fumihiro Kawagoe, Tsuneo Imamoto*

*Department of Chemistry, Faculty of Science, Chiba University, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan, Email: kyoshidafaculty.chiba-u.jp, imamotofaculty.chiba-u.jp

K. Yoshida, S. Horiuchi, N. Iwadate, F. Kawagoe, T. Imamoto, Synlett, 2007, 1561-1562.

DOI: 10.1055/s-2007-982548

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Abstract

Various substituted phenol and benzene derivatives were prepared through RCM-tautomerization and RCM-dehydration protocols without formation of inseparable regioisomers.

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Synthesis of Styrenes Using Ruthenium-Catalyzed Ring-Closing Enyne Metathesis

K. Yoshida, Y. Shishikura, H. Takahashi, T. Imamoto, Org. Lett., 2008, 10, 2777-2780.

A New Synthetic Approach to Phenol Derivatives: Use of Ring-Closing Olefin Metathesis

K. Yoshida, T. Imamoto, J. Am. Chem. Soc., 2005, 127, 10470-10471.

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Key Words

annulations, metathesis, ring closure, ruthenium, tautomerism

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ID: J60-Y2007-2010