An Efficient Synthesis of Nitroalkenes by Alkene Cross Metathesis: Facile Access to Small Ring Systems
Graham P. Marsh, Philip J. Parsons,* Clive McCarthy and Xavier G. Corniquet
*Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, United Kingdom, Email: p.j.parsonssussex.ac.uk
G. P. Marsh, P. J. Parsons, C. McCarthy, X. G. Corniquet, Org. Lett., 2007, 9, 2613-2616.
DOI: 10.1021/ol070557k (free Supporting Information)
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A synthesis of highly functionalized nitroalkenes utilizes a cross metathesis reaction between simple aliphatic nitro compounds and a range of substituted alkenes. This chemistry offers a simple and attractive route to nitroalkenes that would otherwise be difficult to prepare, and that are precursors to various heterocyclic entities.
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