[(NHC)Au^I]-Catalyzed Rearrangement of Allylic Acetates

Nicolas Marion, Ronan Gealageas and Steven P. Nolan*

*Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona, Spain, Email: snolaniciq.es

N. Marion, R. Gealageas, S. P. Nolan, Org. Lett., 2007, 9, 2653-2656.

DOI: 10.1021/ol070843w (free Supporting Information), Corrections: 10.1021/ol800032e

---

Abstract

Gold N-heterocyclic carbene complexes, in conjunction with a silver salt, were found to efficiently catalyze the rearrangement of allylic acetates under both conventional and microwave-assisted heating. The steric hindrance of the ligand bound to gold was found crucial as only bulky ligands permitted the isomerization.

see article for more examples

---

---

Key Words

Overman Rearrangement, Allylic Alcohols, Microwave Synthesis

---

ID: J54-Y2007-2150