Organic Chemistry Portal

Abstracts

Search:

Bromination of Deactivated Aromatics: A Simple and Efficient Method

K. Rajesh, M. Somasundaram, R. Saiganesh* and K. K. Balasubramanian

*Shasun Research Centre, No. 27, Vandaloor-Kelambakkam Road, Keelakottaiyur, Chennai-600 048, India, Email: saiganeshshasun.com

K. Rajesh, M. Somasundaram, R. Saiganesh, K. K. Balasubramanian, J. Org. Chem., 2007, 72, 5867-5869.

DOI: 10.1021/jo070477u (free Supporting Information)


Abstract

Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated sulfuric acid. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics in good yields.

see article for more examples



Key Words

aryl bromides, NBS


ID: J42-Y2007-2360