Diastereoselective Synthesis of Arylglycine Derivatives by Cationic Palladium(II)-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters
Huixiong Dai and Xiyan Lu*
*State Key Laboratory of Organometallic Chemistry, Shanghai
Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu,
Shanghai 200032, China, Email: xylu
mail.sioc.ac.cn
H. Dai, X. Lu, Org. Lett., 2007, 9, 3077-3080.
DOI: 10.1021/ol0711220 (free Supporting Information)
Abstract
A cationic palladium-complex catalyzes the addition of arylboronic acids to N-tert-butanesulfinyl iminoacetates to yield optically active arylglycine derivatives with good yield and high diastereoselectivity. This reaction provides a convenient and efficient method for the synthesis of arylglycine derivatives.
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Key Words
ID: J54-Y2007-2550
