Organic Chemistry Portal

Abstracts

Search:

Diastereoselective Synthesis of Arylglycine Derivatives by Cationic Palladium(II)-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters

Huixiong Dai and Xiyan Lu*

*State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China, Email: xylumail.sioc.ac.cn

H. Dai, X. Lu, Org. Lett., 2007, 9, 3077-3080.

DOI: 10.1021/ol0711220


Abstract

A cationic palladium-complex catalyzes the addition of arylboronic acids to N-tert-butanesulfinyl iminoacetates to yield optically active arylglycine derivatives with good yield and high diastereoselectivity. This reaction provides a convenient and efficient method for the synthesis of arylglycine derivatives.

see article for more examples



Key Words

Amino Acids


ID: J54-Y2007-2550