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Base-Free Mizoroki-Heck Reaction Catalyzed by Rhodium Complexes

Rémi Martinez, Florina Voica, Jean-Pierre Genet* and Sylvain Darses*

*Laboratoire de Synthèse Sélective Organique (UMR 7573, CNRS), Ecole Nationale Supérieure de Chimie de Paris, 11 rue P&M Curie, 75231 Paris cedex 05, France, Email: sylvain-darsesenscp.fr, jean-pierre-genetenscp.fr

R. Martinez, F. Voica, J.-P. Genet, S. Darses, Org. Lett., 2007, 9, 3213-3216.

DOI: 10.1021/ol071098q (free Supporting Information)


Abstract

A base-free rhodium-catalyzed Mizoroki-Heck reaction of potassium aryltrifluoroborates with alkenes in the presence of acetone as green "oxidant" constitutes an interesting alternative to conventional olefinations using aryl halides thanks to the ready availability of organoboranes.

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proposed mechanism



Key Words

Heck Reaction, Olefination, Acetone


ID: J54-Y2007-2660