Nickel(0) Triethyl Phosphite Complex-Catalyzed Allylic Substitution with Retention of Regio- and Stereochemistry
Yasutaka Yatsumonji, Yusuke Ishida, Akira Tsubouchi and Takeshi Takeda*
*Department of Applied Chemistry, Graduate School of
Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo
184-8588, Japan,
Email: takeda-t
cc.tuat.ac.jp
Y. Yatusmonji, Y. Ishida, A. Tsubouchi, T. Takeda, Org. Lett., 2007, 9, 4603-4606.
DOI: 10.1021/ol702122d (free Supporting Information)
Abstract
A nickel(0) triethyl phosphite complex promotes the reaction of allylic acetates with thiols to produce allylic sulfides with retention of configuration without allylic rearrangement. A similar reaction of allylic acetates with alcohols and phenols also proceeds with retention of regio- and stereochemistry.
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Key Words
ID: J54-Y2007-3450
