Microwave-Assisted Transformation of Esters into Hydroxamic Acids
Assunta Massaro, Alessandro Mordini*, Gianna Reginato, Francesco Russo, Maurizio Taddei
*ICCOM-CNR, Dipartimento di Chimica Organica ‘U. Schiff', Via
della Lastruccia 13, 50019 Sesto Fiorentino, Italy,
Email: alessandro.mordini
unifi.it
A. Massaro, A. Mordini, G. Reginato, F. Russo, M. Taddei, Synthesis, 2007, 3201-3204.
DOI: 10.1055/s-2007-990803
Abstract
The reaction of esters with hydroxylamine in the presence of a base under microwave activation provides hydroxamic acids in good yields and purity. The method has been successfully applied to enantiomerically pure esters without loss of stereochemical integrity.
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Key Words
esters, chemoselectivity, hydroxamic acids, microwave reactions
ID: J66-Y2007-3490
